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Example Questions
Example Question #1 :Microbiology
What is the primary effect of botulism toxin?
Nausea and vomiting
Tonic paralysis
Ascending paralysis
Flaccid paralysis
Flaccid paralysis
Botulism toxin inhibits acetylcholine release from the presynaptic nerve terminal, causing flaccid paralysis. Death in botulism exposure is generally due to respiratry failure.Tonic paralysis is the cause of respiratory arrest in other toxicity exposures, such as exposure to tetanus toxin.
Example Question #1 :Microbiology
What organism causes Rocky Mountain spotted fever?
Rickettsia rickettsii
Rickettsia helvetica
Ehrlichia chaffeensis
Borrelia burgdorferi
Rickettsia rickettsii
Rickettsia rickettsiicauses Rocky Mountain Spotted Fever, and is spread by dermacentor ticks. It causes fever, headache, muscle pain, and a rash.Borrelia burgdorferiis associated with Lyme disease, ehrlichia chaffeensisis associated with human monocytotropic ehrlichiosis, andrickettsia helveticais associated (very rarely) with meningitis.
Example Question #1 :Identifying Bacteria
传染性diarrh最常见的原因是什么ea in HIV-positive patients?
Clostridium
Cryptosporidium
Salmonella
Campylobacter
Cryptosporidium
While all of the listed organisms can cause diarrhea,Cryptosporidium,a protozoa, is the most commonly isolated organism in HIV positive patients presenting with diarrhea.
Example Question #2 :Identifying Bacteria
What is the most common infection preceding the development of Guillain-Barré syndrome?
Salmonella
Campylobacter jejuni
Staphylococcus aureus
E. coli
Campylobacter jejuni
30% of cases of Guillain-Barré are preceded by infection by Campylobacter jejuni.There is no known association between Staphylococcus aureus, Salmonella,orE.coliand Guillain-Barré syndrome.
Example Question #1 :Microbiology
All of the following are frequently implicated in epiglottitis except__________.
Campylobacter jejuni
Staphylococcus aureus
Streptococcus spp
H. influenzaetype B
Campylobacter jejuni
The most commonly implicated bacteria in epiglottiits areH. influenzaetype B,链球菌spp,andStaphylococcus aureus.Campylobacter jejuniis a common cause of food poisoning.
Example Question #1 :Microbiology
Which agar would be the best choice option to identify大肠杆菌?
Phenethyl alcohol
Nutrient agar
EMB (eosin methylene blue), because it is selective and differential
Selenium enriched media
EMB (eosin methylene blue), because it is selective and differential
The question requires the knowledge that大肠杆菌is a facultative, Gram negative, lactose fermenting bacteria. EMB (eosin methylene blue), or Mac (MacConkey) media is superior for isolating大肠杆菌because it is both selective and differential. Nutrient agar is neither selective nor differential. Selenium enriched media would not help identify this bacteria becauseEscherichiacolidoes not require this supplemented media to grow. Phenethyl alcohol can be used to select for anaerobic bacteria, which is of no utility in this situation.
Example Question #1 :Bacteria
Which of the following sexually transmitted infections is mismatched with its causative agent?
Syphillis -Treponema pallidum
Gonorrhea -Neisseria gonorrhea
Toxic shock syndrome -Staphylococcus aureus
Genital warts - herpes simplex virus 2
Genital warts - herpes simplex virus 2
Genital warts is caused by human papillomavirus. All other sexually transmitted infection is correctly matched with its causative agent.
Example Question #1 :Identifying Bacteria
Which of the following organisms causes fever, headache, fatigue, myalgia, and buboes?
Staphylococcus aureus
Bacillus anthracis
Yersinia pestis
Borrelia burgdorferi
Yersinia pestis
The question stem describes bubonic plague which is caused byYersinia pestis.Staphylococcus aureuscauses skin infections, toxic shock, and food poisoning.Bacillus anthracis causes anthrax, which is similar to plague, but does not cause buboes.Borrelia burgdorfericauses lyme disease., which presents as rash and arthralgia.
Example Question #2 :Identifying Bacteria
E. coli (Esherichia coli) are primarily found in the colon of humans, but can also cause cystitis. Which of the following best explains why this occurs?
E. coliare obligate anaerobes
E. coliare obligate aerobes
E coliare facultative anaerobes
E. coliare microaerophiles
E coliare facultative anaerobes
The colon is anaerobic and the bladder is aerobic. This fact explains whyE. colinormally lives in an anaerobic environment, but can also survive aerobically. Facultative anaerobes normally live in anaerobic conditions but can adapt to aerobic conditions. Microaerophiles describes bacteria that are obligate aerobes, but are poisoned by high levels of oxygen and thus require specific oxygen levels to grow.
Example Question #2 :Identifying Bacteria
90% of allProteusinfections in human are caused by what organism?
Proteus mirabilis
Proteus myxofaciens
Proteus vulgaris
Proteus penneri
Proteus mirabilis
WhileProteus penneriandProteus vulgarisdo cause opportunistic infections in a small percentage of people, 90% ofProteusinfections in humans are caused byProteus mirabilis.
Proteus myxofaciens只存在于insect hosts and does not infect humans.
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