Given that the hydrolysis of 1 mole of ATP has delta G of, if 2 moles of ATP are hydrolyzed, delta. Reaction D has a delta G of; when coupled with the hydrolization of 2 moles of ATP, delta G will be. As this is negative, it is indicated that this will be a spontaneous reaction, or can proceed without input of energy.

ATP耦合的过程中水解P (a thermodynamically favorable, negative delta G, or spontaneous reaction) is coupled with a thermodynamically unfavorable reaction (a reaction that cannot proceed without energy input).

An endergonic reaction requires input of energy; delta G will be positive. Hydrolysis of ATP, cellular respiration, and catabolism (breakdown of a large molecule) are exergonic processes. The Na+/K+ pump is endergonic, as it requires energy. This process is coupled with ATP hydrolysis to allow it to proceed.

Exergonic reactions are reactions that release energy. Endergonic reactions are reactions that require energy to proceed. Exergonic reactions can occur spontaneously, or are thermodynamically favorable. Endergonic reactions cannot occur spontaneously, or are thermodynamically unfavorable.

ATP hydrolysis is exergonic. ATP phosphorylation is the reverse of ATP hydrolysis, and thus is endergonic.

Through ATP coupling, the hydrolysis of ATP can allow the second, thermodynamically unfavorable reaction to proceed.. As the resulting deltais negative, this will be thermodynamically favorable.

The phosphoanhydride bonds of ATP, or the bonds between phosphate molecules, are high energy. This is due to the close proximity of positively charged phosphate and negatively charged oxygen; these charges repel. Also, there is resonance stabilization of the products of ATP hydrolysis (ADP and Pi); thus ADP is more stable than ATP. Additionally, entropy is increased when ATP is hydrolyzed; the second law of thermodynamics states that the entropy of a system always increases.

ATP consists of 3 phosphate groups, a ribose sugar, and adenine.

ATP is unstable; there is close proximity of positively charged phosphate and negatively charged oxygen; these charges repel. When hydrolyzed, delta G is <0 (exergonic). ATP is not used for long term-energy storage, as it is unstable. When hydrolyzed, a phosphoanhydride bond is broken.

When ATP is hydrolyzed and a phosphoanhydride bond is broken, ADP and a phosphate are the products. ADP then has 2 phosphate groups.